高伟
点击数:更新日期: 2021-04-26
高伟教授、硕士生导师
电子邮箱:gaowei_box@163.com
办公电话:010-62338136
研究方向
生物大分子结构与功能
教育工作经历
2001.9–2005.1中国科学院生物物理所,博士
1998.9–2001.7中国农科院生物技术所,硕士
1987.9–1991.7郑州大学,学士
2005年-至今江南的注册网址理学院 副教授、教授
主讲课程
《生物物理学》、《大学物理学》、《物理与人类文明》
奖励及荣誉称号
教育部新世纪优秀人才
北京市第五届青年教师基本功比赛三等奖
校优秀硕士、本科生导师
学术/社会兼职
protein and peptide letters审稿人
工作及成果展示
科研项目
1.江南的注册网址重大科研成果,中国传统菊花品种起源和进化的遗传研究,16万,在研,参加.
2.江南的注册网址青年教师科学研究中长期项目,林业测量仪器平台建设与应用,50万元,在研,参加.
3.国家自然科学基金面上项目,31070651、植物特有的类神经钙素B与激酶复合物(CBL1-CIPK23)的晶体结构测定及功能研究,35万元,主持.
4.国家自然科学基金面上项目,30970578、植物特有的类神经钙素B蛋白及相互作用激酶复合物的晶体结构测定与抗性功能关系的研究,8万元,主持.
5.国家自然科学基金重点项目,30730077调控杨树耐旱节水性状的功能基因组学研究、150万元、参加.
6.教育部新世纪优秀人才, 2008年,林业科学.
7.国家林业局重点项目,2006-59、抗杨树虫害的蛋白酶抑制剂类制剂的开发研究,20万元、主持.
发表论文
(1) Salinas, Gustavo(*); Gao, Wei(#); Wang, Yang; Bonilla, Mariana; Yu, Long; Dai,Shaodong(*) The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I) , ANTIOXIDANTS & REDOX SIGNALING, 2017.12.20, 27(18): 1491~1504
(2) Lu, Fang; Zhang, Bei; Liu, Yong; Song, Ying; Guo, Gangxing; Feng, Duo;Huang, Huoqing; Yang, Peilong; Gao, Wei(*) ; Guo, Sujuan(*) ; Yao, Bin(*) Crystallization and X-ray diffraction analysis of native and selenomethionine-substituted PhyH-DI from Bacillus sp HJB17 , ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2017.11, 73:607~611
(3) Zhao Qihong; Liu Jie; Xu Xiao; Xu Qian; Gao Wei(*); Xu Jichen；PicW orthologs from spruce with differential freezing tolerance expressed inEscherichia coli , INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017.8,101: 595~602
(4)Liu Yong; Lu Fang; Guo Gang-Xing; Feng Duo; Zhang Bei; Gao Wei ; BiRu-Chang(*), Crystallization and Preliminary Crystallographic Analysis ofThioredoxin-dependent Thiol Peroxidase (SF2523) From Shigella flexneri 2a str.301 ,生物化学与生物物理进展, 2017.3, 44(3): 253~258
(5)Lu, Fang ; Guo, Gangxin; Li, Qianqian; Feng, Duo; Liu, Yong; Huang,Huoqing; Yang, Peilong; Gao, Wei(*); Yao, Bin(*),Preparation, purification,crystallization and preliminary crystallographic analysis of dual-domain beta-propeller phytase from Bacillus sp HJB17 , Acta Crystallographica Section F-Structural Biology Communications, 2014.12, 70: 1671~1674
(6) Shang, Guijun; Feng, Duo; Lu, Fang; Zhang, Hongjie; Cang, Huaixing; Gao, Wei(*); Bi, Ruchang,Purification, crystallization and preliminary crystallographic analysis of a ribosome-recycling factor from Thermoanaerobacter tengcongensis (TteRRF) , ACTA CRYSTALLOGRAPHICA SECTIONF-STRUCTURAL BIOLOGY COMMUNICATIONS, 2014.5, 70: 588~591
(7)Shang, Guijun; Cang, Huaixing; Liu, Zhijie; Gao, Wei ; Bi, Ruchang,(*)Crystallization and preliminary crystallographic analysis of a calcineurin B-likeprotein 1 (CBL1) mutant from Ammopiptanthus mongolicus , Acta Crystallographica Section F-Structural Biology and Crystallization Communications,2010.12, 66: 1602~1605
(8)Yuan, Daopeng; Wang, Qihai; Gao, Wei ; Sheng, Fanyi; Zhang, Zhanyu;(*)Lu, Qingyu; Cang, Huaixing; Bi, Ruchang, Cloning, expression, purification,characterization, crystallization and X-ray diffraction of bifunctionalpyrimidine deaminase/reductase from Shigella flexneri 2a , Protein and PeptideLetters, 2007,14(9)925-927
(9)Gao, Wei; Starkov, Vladislav G.; He, Zi-xuan; Wang, Qi-hai; Tsetlin,Victor I.; Utkin, Yuri N.; Lin, Zheng-jiong; Bi, Ru-chang,(*) Functions,structures and Triton X-100 effect for the catalytic subunits of heterodimeric phospholipases A(2) from Vipera nikolskii venom , Toxicon, 2009.11, 54(6):709~716
(10) Li, Shu-Xing ; Tong, Yong-Ping; Xie, Xiao-Cong; Wang, Qi-Hai; Zhou,(#)Hui-Na; Han, Yi; Zhang, Zhan-Yu; Gao, We; Li, Sheng-Guang; Zhang, Xuejun C.;Bi, Ru-Chang(*) Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis , Journal of Molecular Biology, 2007.3.9, 366(5):1603~1614
专利
(1)高伟;鲁芳;李倩倩;郭刚兴,一种大量制备双功能域β-折叠桶植酸酶二体的方法, 2014.4.23,中国, CN201410006180.4 (专利)
(2)高伟,一种豇豆胰蛋白酶抑制剂基因、及其应用、大量制备豇豆胰蛋白酶抑制剂的方法, 2010.12.8,中国, CN201010590327.0 (专利)
