何晓靑�/h1>

• 植物与微生物组的互作机制（微生物如何影响宿主健康（�/span>

network mapping）等关联分析方法，全基因组角度挖掘塑造植物微生物组的植物枢纽基因, 筛选关键微生物类群并解析微生物组对植物表型形成的贡献，量化植物-微生物组的相互影响，探究植物与微生物组互作调控机�? 系统地研究微生物组在植物抗病、营养吸收、生长发育等过程中的功能和作用、�/span>

• 微生物群落构建机制及功能调控（微生物如何维持生态功能）

建立了研究不同生态系统（山水林田湖草沙）中微生物群落构建机制的方法体系（微生物结构及多样性、共发生网络模式、群落组装机制、功能潜力等）。探究不同生态系统微生物多样性产生和维持的机制，解析微生物的环境适应性规律，揭示核心微生物的关键态系统功能，阐明网络复杂度决定微生物功能发挥的机制。拟拓展对微生物群落形成和适应性规律的认识，为微生物群落构建与功能调控提供理论依据与途径、�/span>

• 合成微生物菌群（SynComs）及生态修夌�/span>

利用上述成果，应用合成菌群改善根际微生物组并促进植物健康；并针对水体常见问题（黑臭、水华、青苔），利用微生物对水体的净化作用，研发了系列净水制剂。在污染水体中使用特定的微生物菌剂，配合生态工法设计和水生植物栽植,形成以微生物菌剂为核心的水下生态修复及水体生态系统构建技术。操作简单，成本低廉，效果明显，配合水生植物栽植，模拟自然的驳岸，既能保证水体水质，也能营造良好的景观效果

1995-1999华中农业大学 学士

1999-2002华中农业大学硕士

2004-2007中国科学院生态环境研究中� 博士

2002-�?nbsp; 北京林业大学 任职

2011.5-2012.5瑞士联邦水科学与技术研究所＇�/span>EAWAG� 访问学者（博士后）

2013.7-2013.8美国密歇根州立大�?nbsp; 访问学耄�/span>

• 全基因组系统作图（systems mapping）研究三种细菌种间互作遗传机制，国家自然科学基金面上项目，主持，2020.1.1-2023.12.31、�br /> 再生水补给河道微生物功能特征研究，横向课题，主持�?022.04.25-2022.12.31
  喀斯特地区石漠化综合治理技术集成与应用，中国科学院科技服务网络计划（STS计划）子课题，主持，2018.1.1-2019.6.30、�br /> 典型城市饮用水体系中轮状病毒的分布与健康风险，国家自然科学基金青年项目，主持�?012.1.1-2014.12.31、�br /> 重点流域典型水源地风险污染物筛查和评价，水利部公益性行业专项经费项目，子课题负责人�?012.1.1-2014.6.30、�br /> 水环境监测的新技术、新方法研发与应用示范，国家水体污染控制与治理科技重大专项，专题负责人�?010.1.1-2012. 12.31、�br /> 参加国家自然科学基金项目-基于植物和微生物筛选的人工景观水体自净技术与应用 2018-2020
  参加北京林业大学科技创新计划-冬眠中达乌尔黄鼠肠道微生物调控能量代谢研� 2018-2019
  参加北京林业大学青年教师科学研究中长期项�?森林生物资源利用—森林食品资源开发与综合利用 2015-2020

  参加北京林业大学基础科学研究团队专项计划-森林资源与环境微生物的应用基础研究 2012-2016

论文９�/span>

• Kaihang Li, Kexin Cheng, Haochen Wang, Qi Zhang, Yan Yang, Yi Jin, Xiaoqing He* and Rongling Wu. Disentangling leaf-microbiome interactions in Arabidopsis thaliana by network mapping. Frontier in plant science,2022, 13:996121.（二区，IF�?.627（�br /> Yan Yang, Kexin Cheng, Kaihang Li, Yi Jin, Xiaoqing He*. Deciphering the diversity patterns and community assembly of rare and abundant bacterial communities in a wetland system. Science of The Total Environment. 2022, 838, Part 4,156334（二区，IF�?0.753（�br /> Xiaoqing HE, Qi ZHANG, Beibei LI, Dr Yi JIN, Libo JIANG, Rongling WU. Network mapping of root-microbe interactions in Arabidopsis thaliana. npj biofilms and microbiomes, 2021, 7,72.（二区，IF�?.462（�br /> Dengcheng Yang, Xuyang Zheng, Jiang Libo, Ye Meixia, Xiaoqing He, Yi Jin, Rongling Wu. Functional mapping of phenotypic plasticity of Staphylococcus aureus under vancomycin pressure. Frontier in microbiology, 2021,12:696730. （二区，IF�?.64（�br /> Yang, D., Jin, Y., He, X. et al. Inferring multilayer interactome networks shaping phenotypic plasticity and evolution. Nature communications 2021, 12, 5304. （一区，IF�?7.694（�br /> Qi Zhang, Yajing Liang, Weiwen Kong, Dongyang Wang, Yi Jin, Yu Ye, Xiaoqing He*, Libo Jiang*. Transcriptional differentiation driving Cucumis sativus–Botrytis cinerea interactions based on the Skellam model and Bayesian networks. AMB Express, 2021,11, 138 . (IF= 4.126（�br /> Yajing Liang, Beibei Li, Qi Zhang, Shilong Zhang, Xiaoqing He*, Libo Jiang,Yi Jin. Interaction analyses based on growth parameters of GWAS between Escherichia coli and Staphylococcus aureus. AMB Express,2021, 11, 34 (IF= 4.126).
  Zheng Xuyang, Bai Jun,Ye Meixia, Liu Yanxi, Jin Yi, He Xiaoqing*. Bivariate genome-wide association study of the growth plasticity of Staphylococcus aureus in coculture with Escherichia coli. Applied Microbiology and Biotechnology ,2020�?04, 5437�?447. (二区，IF=4.813（�br /> Mengdi Rong, Xuyang Zheng, Meixia Ye, Jun Bai, Xiangming Xie, Yi Jin，Xiaoqing He*. Phenotypic Plasticity of Staphylococcus aureus in Liquid Medium Containing Vancomycin. Frontier in microbiology, 2019,10:809.（二区，IF=4.259（�br /> Libo Jiang#, Xiaoqing He#, Yi Jin#, Meixia Ye#, Rongling Wu. A competition-cooperation mapping framework of community dynamics. Nature communications, 2018, 9: 3010.( 一区，IF=12.124)
  Xiaoqing He#, Yi Jin#, Meixia Ye#, Nan Chen, Jing Zhu, Jingqi Wang, Libo Jiang, Rongling Wu*. Bacterial genetic architecture of ecological interactions in co-culture by GWAS-Taking Escherichia coli and Staphylococcus aureus as an example. Frontier in microbiology, 2017, 8 :2332.（二区，IF=4.08（�br /> YubingWang, XiaoliLi, LiboJiang, WentaoHan, XiangmingXie, YiJin*, Xiaoqing He* and RonglingWu*. Novel Mutation Sites in the Development of Vancomycin- Intermediate Resistance in Staphylococcus aureus. Frontier in microbiology, 2017, 7 :2163.（二区，IF=4.08（�br /> Tingting Liu,Weiwen Kong,Nan Chen,Jing Zhu. Jingqi Wang,Xiaoqing He*. Bacterial characterization of Beijing drinking water by flow cytometry and MiSeq sequencing of the 16S rRNA gene. Ecology and Evolution, 2016, 6(4):923-934. (IF=2.3).
  Weiwen Kong, Nan Chen, Tingting Liu, Jing Zhu, Jingqi Wang, Xiaoqing He*, Yi Jin. Large-scale transcriptome analysis of cucumber and Botrytis cinerea during infection. PLOS One, 2015, 10(11): e0142221. (IF=3.2).
  Xiaolu Liu, Jingqi Wang, Tingting Liu, Weiwen Kong, Xiaoqing He*. Effects of assimilable organic carbon and free chlorine on bacterial growth in drinking water. PLOS One, 2015, 10(6): e0128825. (IF=3.2).
  Yu-Mei Wei, Jing-Qi Wang, Ting-Ting Liu, Wei-Wen Kong, Nan Chen, Xiao-Qing He*, Yi Jin. Bacterial communities of Beijing surface waters as revealed by 454 pyrosequencing of the 16S rRNA gene. Environmental Science and Pollution Research, 2015, 22(16):12605-14. (IF=2.8).
  Boyun Yang, Xiaoqing He* et al. Rapid and sensitive detection of human astrovirus in water samples by loop-mediated isothermal amplification with hydroxynaphthol blue dye. BMC microbiology, 2014, 14(8) (IF=3.1).
  Xiaoqing He; Li Cheng; Deyou Zhang. Molecular detection of three gastroenteritis viruses in urban surface waters in Beijing and correlation with levels of fecal indicator bacteria. Environmental Monitoring and Assessment,2012,184(9): 5563-5570( IF=1.6).
  Xiaoqing He; Li Cheng; Deyou Zhang; Xiangming Xie; Donghong Wang; Zijian Wang. One-year Monthly Survey of Rotavirus, Astrovirus and Norovirus in Three Sewage Treatment Plants (STPs) in Beijing, China and Associated Health Risk Assessment. Water Science and Technology. 2011,63�?�?191-198. (IF=1.1).
  He XQ, Cheng L, Li W, Xie XM, Ma M, Wang ZJ. Detection and distribution of rotavirus in municipal sewage treatment plants (STPs) and surface water in Beijing. Journal of Environmental Science and Health, Part A.2008, 43�?）：424-429. (IF=1.3).
  He XQ, Cheng L, Zhang DY, Li W, Xie XM, Ma M, Wang ZJ. First Molecular Detection of Group A Rotaviruses in Drinking Water Sources in Beijing，China. Bulletin of Environmental Contamination and Toxicology, 2009, (83):120�?24. (IF=1.1).
  Mingjia Yang, Xiangming Xie, Caixia Zheng,Fangqiu Zhang,Xiaoqing He,Zhiru Li. Agrobacterium tumefaciens-mediated genetic transformation of Acacia crassicarpa via organogenesis. Plant Cell, Tissue & Organ Culture, 2008, (95): 141-147. ( IF=1.3).
  Mingjia Yang, Xiangming Xie, Xiaoqing He, Fangqiu Zhang. Plant regeneration from phyllode explants of Acacia crassicarpa via organogenesis. Plant Cell, Tissue & Organ Culture, 2006(85): 241-245 . (IF=1.3).
  李凯�?王浩臢�程可忂�杨艳;金一;何晓�?全基因组关联分析研究植物与微生物组互作遗传机�?生物技术通报�?022，已接收.
  杨艳,王浩,李凯�?李贝�?张琦,金一,何晓�? 长江三峡上游水域细菌群落结构与功能预�? 微生物学�?2022, 62(4): 1401-1415.
  李贝�? 朱晗�? 张琦, 杨鹏, 金一, 何晓�? 影响微生物互作的重要基因研究进展：以大肠杆菌为例. 微生物学通报�?021, 48(9): 3071-3082.
  张琦，梁雅静，张宇馨，陈玲慧，韩钟娆，李贝贝，金一，何晓青*. 基因编辑技术对大肠杆菌yjjW 基因点突变的两步法策�? 微生物学�?2021, 61(1):183-194
  梁雅静，何晓�?、金一、姜立波，叶梅霞，邬荣领. 二代测序技术（NGS）结合遗传统计模型在微生物分子生态学中的研究进展. 中国科学：生命科�? 2020,2:217-214.
  张佐然，李金婷，梁雅静，张琦，金一，何晓青*. 利用系统作图(Systems mapping)研究大肠埃希菌和金黄色葡萄球菌的互作遗传机制. 微生物学通报 2019,46(2):292-300
  朱璟, 王峥鉴， 张佐�? 李金�? 梁雅�? 金一, 何晓�?. 不同培养条件下金黄色葡萄球菌表型可塑性研�? 微生物学杂志�?019�?9(4):10-16.
  陈南，朱璟，叶梅霞，金一，何晓青*，邬荣领. GWAS研究大肠杆菌和金黄色葡萄球菌种间互作进化机制.微生物学�? 2017�?7(4): 526-538.
  刘婷婷，孔维文，王敬琦，何晓�?. 基于流式细胞术研究管网水中细菌的稳定�?应用与环境生物学�?2016, 22�?）：1136-1142.
  王敬琦，孔维文，刘婷婷，陈南，杨柏云，何晓青*.基于esp基因和JCV标记的MST方法在五大流域典型水源地中的应用.生态毒理学�? 2015,10(6):246-252.
  刘晓露，王敬琦，张柏林，何晓�?. 可同化有机碳和余氯对饮用水中细菌活性的共同影响.安全与环境学�?2014, 14(3):198-201.
  杨柏�?韦玉梅，何晓�?�? 基于LAMP的人轮状病毒检测方法及其在水环境中的应�?安全与环境学�?2013,13�?（�113-118.

  杨丽,程莉，何晓青*�? 环介导等温扩增技�?LAMP)检测人星状病毒方法的建立及其在再生水检测中的应�?生态毒理学�? 2011, 6:595-602.

参加会议９�/span>

• 何晓�?Nature会议(HARNESSING THE PLANT MICROBIOME), 2022.Network mapping of root-microbe interactions in Arabidopsis thaliana. (线上Poster)
  何晓�?网络作图（network mapping）研究植�?微生物组互作机制2021土壤学会土壤生物和生化专业委员会暨土壤生物多样性与生物化学过程研讨�? 合肥（口头报告）
  何晓�?基于全基因组系统作图（systems mapping）的细菌种间互作遗传机制研究. 微生物生态专业委员会2018年学术年会暨微生物生态学国际研讨�? 2018，广州（口头报告（�br /> Boyun Yang, Xiaoqing He, Zijian Wang. Rapid and sensitive detection of human astrovirus in water samples by loop-mediated isothermal amplification with hydroxynaphthol blue dye. Water Convention 2014, Singapore (Poster).
  Xiaoqing He; Li Cheng; Deyou Zhang; Zijian Wang. One-year Monthly Survey of Rotavirus, Astrovirus and Norovirus in Three Sewage Treatment Plants (STPs) in Beijing, China and Associated Health Risk Assessment. 2010 International Water Congress, Montreal, Canada (Oral Presentation) .

  Xiaoqing He, Li Cheng, Deyou Zhang, Xiangming Xie. Monitoring of Rotaviruses in Surface Waters in Beijing, China, and the Potential Health Risk. 2010 SETAC Europe 20th Annual Meeting ,Sevilla, Spain(Poster).